Title：Effect of mifepristone on patients after laparoscopic myomectomy
作者：李碧
关键词：米非司酮,腹腔镜子宫肌瘤剔除术,血清性激素,复发率
论文类型：期刊论文
论文来源：长治医学院学报 2019
摘要：目的：观察米非司酮对腹腔镜子宫肌瘤剔除术后患者的临床疗效。方法：102例腹腔镜子宫肌瘤剔除术患者随机分为两组，每组51例。对照组采用单腹腔镜子宫肌瘤剔除术，观察组在对照组的基础上加用米非司酮。比较两组临床疗效、血清性激素（E2、LH、P、FSH）、复发率及并发症。结果：与对照组比较，观察组E2[（261.23±34.26）vs（497.56±62.15）pmol/L，P[（3.84±0.46）vs（10.88±1.23）nmol/L，FSH[（10.38±1.20）vs（17.62±2.11）μg/L，LH[（15.37±1.85）vs（22.57±2.65）IU/L]均低于对照组，观察组总有效率（98.04%）显著高于对照组（84.84.04%），显著高于对照组（98.04%），总有效率（98.04%）显著高于观察组（98.04%），复发率（3.92%）差异有统计学意义有统计学意义（P<；0.05）。结论：米非司酮治疗腹腔镜子宫肌瘤切除术后可提高血清性激素水平，降低复发率，安全性高，临床疗效显著。
Abstract：Objective: To observe the clinical effect of mifepristone on patients after laparoscopic myomectomy. Methods: 102 patients who underwent laparoscopic myomectomy were randomly divided into two groups, 51 in each group. The control group was treated with single laparoscopic myomectomy, and the observation group was treated with mifepristone on the basis of the control group. The clinical effects, serum sex hormones (E2, LH, P, FSH), recurrence and complications were compared between the two groups. Results: compared with the control group, the E2 [(261.23 ± 34.26) vs (497.56 ± 62.15) pmol / L, P [(3.84 ± 0.46) vs (10.88 ± 1.23) nmol / L, FSH [(10.38 ± 1.20) vs (17.62 ± 2.11) μ g / L, LH [(15.37 ± 1.85) vs (22.57 ± 2.65) IU / l] of the observation group were lower than the control group, the total effective rate of the observation group was significantly higher (98.04%) than the control group (84.84.04%) significantly higher (98.04%) than the total effective rate of the control group (98.04%) was significantly higher than the total effective rate of the observation group (98.04%).31%, recurrence rate (3.92%) ）The difference was statistically significant (P & lt; 0.05). Conclusion: mifepristone treatment after laparoscopic myomectomy can improve the level of serum sex hormone, reduce the recurrence rate, and has a high safety and significant clinical effect.
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标签：米非司酮论文; 腹腔镜子宫肌瘤剔除术论文; 血清性激素论文; 复发率论文;