Title：The effect of combination of kaglitazine and insulin glargine on the first diagnosis of type 2 diabetes mellitus
作者：夏芳,阿荣,叶立英,洪挺,王斌,胡咏梅
关键词：型糖尿病,卡格列净,甘精胰岛素
论文类型：期刊论文
论文来源：浙江实用医学 2019
摘要：目的探讨卡格列净联合甘精胰岛素对2型糖尿病首次诊断的影响。方法将62例2型糖尿病患者随机分为两组：第一组用卡格列嗪治疗，第二组用阿卡波糖治疗12周。观察治疗过程中胰岛素、胰岛素、低血糖等不良反应。结果两组空腹血糖（FBG）、餐后2小时血糖（PBG）、糖化血红蛋白（HbA1c）均明显低于治疗前（P<；0.05）。caglejing组BMI显著低于对照组（P<；0.05）。两组低血糖发生率无显著性差异（P>0.05）。结论卡格列净联合甘精胰岛素能有效控制初诊2型糖尿病患者血糖水平和体重，降低胰岛素用量，安全。
Abstract：Objective to investigate the effect of caglejing combined with insulin glargine on the first diagnosis of type 2 diabetes. Methods 62 patients with type 2 diabetes were randomly divided into two groups: the first group was treated with carboglizine and the second group was treated with acarbose for 12 weeks. During the treatment, the adverse reactions such as insulin, insulin and hypoglycemia were observed. Results fasting blood glucose (FBG), 2-hour postprandial blood glucose (2-hour PBG), HbA1c were significantly lower in the two groups than before treatment (P & lt; 0.05). BMI of caglejing group was significantly lower than that of the control group (P & lt; 0.05). There was no significant difference in hypoglycemia between the two groups (P & gt; 0.05). Conclusion the combination of caglejing and insulin glargine can effectively control the blood glucose level and body mass of the first diagnosed type 2 diabetic patients, and reduce the insulin dosage, which is safe.
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